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Providers > Physicians > James H. Finigan
My research focuses on how cells of the lung adhere and how cell-cell junctions are altered during lung injury and repair. This process is relevant to numerous pulmonary diseases including acute lung injury as well as lung cancer initiation and progression.
2010: BLS, ACLS, Colorado License
2008: Critical Care Medicine
2007: Pulmonary Medicine
2006: Medical License: Ohio
2003: American Board of Internal Medicine
Assistant Professor, University of Colorado, Division of Pulmonary and Critical Care Medicine
American Association for Cancer Research
American Thoracic Society
Pulmonary Circulation Assembly
Finigan JH, Dudek SM, Singleton PA, Chiang ET, Jacobson JR, Camp SM, Ye SQ, Garcia JG. Activated protein C mediates novel lung endothelial barrier enhancement. JBC 2005;280:17286-92.
Abdulnour RE, Peng X, Finigan JH, Han EJ, Hasan EJ, Birukov KB, Reddy SP, Watkins III JE, Kayyali US, Garcia J GN, Tuder RM, and Hassoun PM. Mechanical stress activates xanthine oxidoreductase through MAP Kinase-dependent pathways. AJP: Lung Cellular and Molecular Physiology. AJP: Lung Cellular and Molecular Physiology. 2006;291(3):345-53.
Finigan JH. The Coagulation System and Pulmonary Endothelial Function in Acute Lung Injury. Microvascular Research. 2009; Jan;77(1):35-8.
Finigan JH, Boueiz A, Wilkinson E, Damico R, Skirball J, Pae HH, Damarla M, Hasan E, Pearse DB, Reddy SP, Grigoryev DN, Cheadle C, Esmon CT, Garcia JG, Hassoun PM. Activated protein C protects against ventilator-induced lung injury. Am J Physiol Lung Cell Mol Physiol. 2009; 296(6):1002-11.
Lin Z, Natesan V, Shi H, Dong F, Kawanami D, Mahabeleshwar GH, Atkins GB, Finigan JH and Jain MK. KLF2 regulates endothelial barrier function. Arterioscler Thromb Vasc Biol. 2010;30(10):1952-9.
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