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Providers > Researchers > Donald Bellgrau
Immunobiology of autoimmunity and cancer. We are focused on the role of peripheral T cell regulation in the generation of autoimmunity and development of autoreactivity that might be of benefit as a tumor therapy. We are also studying a whole yeast based biologic.
Bellgrau, D. 2005 Can getting excited over nothing provoke autoimmunity? Adv. Exp. Med. Biol. 552:311-6.
Lu, Y., Bellgrau, D., Dwyer-Nield, L.D., Malkinson, A.M., Duke, R.C., Rodell, T.C. and Franzusoff, A. 2004. Mutation-selective tumor remission with Ras-targeted, whole yeast-based immunotherapy. Cancer Research 64:5084-88.
Lang, J., Kominski, D., *Bellgrau, D. *Scheinman, R (*equivalent senior authors) 2004. Partial activation leads to premature death of T cells harboring an Ian gene mutation. Eur. J. of Immunology 34, 2396-406.
Modiano, J.F.; Sun, J., Lang, J., Vacano, G., Patterson, D., Chan, D.Franzusoff, A.,Gianani, R.,., Meech, S.J., Duke, R. and Bellgrau, D. 2004 Fas ligand dependent suppression of autoimmunity via recruitment and subsequent termination of activated T cells. Clinical Immunology 112:54-65.
Moore, J., Scheinman, R. and Bellgrau, D. 2001 The generation of a novel T cell activation state controlled by a diabetogenic gene. J. of Immunology 166:241-248.
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Link to PubMed for more papers
1980-1983: Member of the Scientific Staff, The Basel Institute for Immunology
Member Comparative Medicine Study Section Founding Scientist, GlobeImmune Inc
Professor of Immunology and Medicine, Program Leader in Immunology/Immunotherapy
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