Cell Biology

David W.H. Riches, Phd, Division Head

David W.H. Riches, PhD
Division Head

What do we do? The Program in Cell Biology is a Division in the Department of Pediatrics. Its mission is to foster and support cutting-edge basic and translational research into the biology and physiology of lung cells, innate and adaptive immune cells, and the signaling pathways that regulate their function.

The Division is comprised of 15 full time primary faculty members with wet lab-based multi-disciplinary research programs focused broadly on lung injury, inflammation, cell biology, immunology, development, remodeling, repair and lipid mediator biology. These specialties have translational connections to acute lung injury, asthma, COPD, pulmonary fibrosis, cystic fibrosis and lung cancer. Several faculty members from the Pediatric Pulmonary and Allergy/Immunology Divisions, as well as the Departments of Medicine and Biomedical Research have secondary appointments in the Program in Cell Biology.

The Program in Cell Biology is led by David W.H. Riches, Ph.D.

Faculty

Joint Faculty Members

Education

Cell Biology faculty members are actively involved in training and teaching. Most faculty members recruit and train post-doctoral fellows in their own labs. All faculty members have adjunct faculty appointments at the University of Colorado and, upon appointment to the Graduate School, are able to train graduate students.

Most graduate student training and mentorship opportunities are through the closely aligned Department of Immunology and Microbiology where Cell Biology faculty teach, serve as course directors, Chairs and members of numerous graduate student preliminary exam, comprehensive exam and thesis committees. Graduate student teaching and training opportunities also exist in the Departments of Pharmacology, Pathology, Cell and Development Biology and within the School of Pharmaceutical Sciences and Toxicology.

In addition, many clinician fellows from the Pulmonary Fellowship Program in the Division of Pulmonary Sciences and Critical Care Medicine train in labs of Cell Biology faculty members. Many of the pulmonary fellows, post-doctoral fellows and graduate students who have trained with Cell Biology faculty members have subsequently established their own independent NIH-funded research careers. Others have gone on to assume leadership positions at Universities across the US and overseas.

Research

All Primary Cell Biology faculty with the exception of Drs. Reynolds and Frazer-Abel have research labs.

We are involved in research, but do not conduct clinical trials.

Faculty members and their labs have full access to extensive Institutional Core Resources supporting flow cytometry, cell sorting, confocal and real time live cell fluorescent imaging, and transcriptomic, genomic and epigenetic analysis/sequencing.

The Institution maintains an outstanding AAALAC-accredited vivarium, a state of the art mouse genetics facility capable of creating genetically modified mice, protein biochemistry and X-ray crystallography facilities and a full service histology core. Cell biology faculty members also have access to the Institutional Biorepository containing over 6000 samples of serum, blood and BAL linked to clinical information through the research database.

Related Programs

Cell Biology faculty members are highly collaborative across the Division, Department, and at an inter-Departmental level. They also collaborate and interact with faculty at the University of Colorado Denver. These collaborations and interactions include research projects, training and teaching opportunities as well as social interactions. Cell Biology faculty members also interact on a more or less weekly basis at the many seminars based at National Jewish or at the University of Colorado Anschutz Medical Campus. 

Cell Biology Faculty utilized all of the basic science related cores as well as the Biobank and Database at National Jewish.

 

Last Updated: 8/2015

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