Steroid Therapy and Nutrition
When you are on systemic (oral or intravenous) steroids (corticosteroids) at a 7.5 mg dose or more daily, it can affect nutrition.
- Steroid therapy has the potential to interfere with the normal absorption and utilization of specific nutrients, including calcium, potassium, sodium, protein, and vitamins C and D.
- A dramatic increase in appetite can occur. Focusing on low calorie foods can prevent extreme weight gain.
- Steroids may irritate the stomach and should not be taken on an empty stomach.
- It is important to choose a varied diet that meets the basic Food Guide Pyramid guidelines. Include healthy foods to help counteract steroid side-effects.
Review the following table to learn how steroids interfere with certain nutrients and how you can compensate for this in your diet.
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Calcium - 99% of this mineral is deposited in your bones and teeth. 1 % is in blood and tissues.
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Impaired calcium absorption.
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Bones may become thin and brittle.
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Increase intake of dietary calcium. Take a calcium supplement if needed. Maintain good calcium intake when off steroids to build up bone mass.
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Potassium - A mineral that regulates muscle contraction and heartbeat.
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Impaired potassium absorption.
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Low blood potassium causes irregular contractions in muscle and heart tissue and may cause fatigue.
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Eat a varied diet including two potassium-rich sources daily, such as: orange juice, apricots, bananas, cantaloupe, baked potatoes, and tomatoes. Take potassium supplements only when prescribed by your physician.
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Sodium - A mineral used in fluid balance and nerve conduction.
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Causes sodium retention.
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Leads to fluid retention and possibly high blood pressure.
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Limit use of salt, condiments, convenience foods, and salted snacks. Choose fresh, less processed foods.
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Protein - Used to maintain muscles, blood, and immune system.
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Breaks down muscle tissue and protein reserves.
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Weak muscles, low resistance to infection, and poor wound healing.
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Eat a well-balanced diet including a protein source at each meal plus dairy products.
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Vitamin D- Helps the bones absorb calcium.
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Inactivates vitamin D so the body cannot use it as well.
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Bones cannot absorb as much calcium so they may become thin and brittle.
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Drink milk at meals. A standard dose multivitamin-mineral supplement contains 400 IU's vitamin D. Short periods of sun exposure without sunscreen activates vitamin D synthesis in skin.
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Vitamin C- Builds tissues and bones and is a strong antioxidant.
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Depletes body stores of vitamin C.
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Less resistance to infections. Poor wound healing.
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Eat a well-balanced diet including citrus fruits, juices, potatoes, and broccoli. A multiple vitamin-mineral supplement also contains vitamin C.
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Cholesterol - A basic component of many body hormones.
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May increase amount of cholesterol in the blood.
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High blood cholesterol.
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Decrease the amount of cholesterol and saturated fats in your diet. Use mono-unsaturated oils (i.e. canola or olive). Limit egg yolks to 4 per week. Maintain healthy body weight.
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Review the following table to learn how steroids can affect your body and how you can compensate for these changes.
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Change in appetite.
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Stimulates a feeling of hunger.
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Increased appetite and weight gain.
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Increase physical activity. Drink plenty of water. Eat low calorie foods such as fresh fruits and vegetables. Focus on lower calorie foods if you are eating a larger volume of food. Keep a food diary to track intake.
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Increased blood sugar.
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Body is less able to utilize insulin or regulate blood glucose.
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High blood glucose levels.
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Maintain healthy body weight. Eat consistent meals and snacks. Cut back on sweets. Increase physical activity.
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Stomach (gastric) irritation.
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Increases stomach acid.
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May cause frequent stomachaches, reflux, and ulcers.
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Avoid overeating. Eat breakfast and do not skip meals. Take medication with a small amount of food. Limit caffeine. Limit dietary fat. Avoid late night eating.
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Change in appearance.
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Fluid and weight shifts to face, abdomen, and trunk of body.
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Puffy, overweight appearance although arms and legs may be thin.
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Not totally avoidable - a temporary fluid weight gain of 10 pounds is to be expected. Control weight gain by limiting sodium and calories Include high potassium foods (i.e.. fresh fruits, vegetables, and whole grains).
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This information has been approved by Carrie Gleeksman, MS, RD (April 2008).