Donna L. Bratton, MD
Dr. Donna Bratton is a pediatric allergy & immunology researcher focused on cellular and molecular mechanisms in allergy, asthma, immunity and inflammation.
Special Interests
Dr. Bratton’s clinical and research interests span the areas of cellular and molecular mechanisms in allergy, asthma, innate immunity, and inflammation. Her laboratory investigates endogenous signals for the resolution of inflammation, including lipid mediators and signals generated by dying inflammatory cells, with the goal of exploiting such signals therapeutically in inflammatory conditions.
Education
Education
- 1976 - 1980
- Vanderbilt University Medical School (Nashville, TN), MD
Residency
- 1980 - 1983
- Vanderbilt University (Nashville, TN), Intern and Resident: Pediatric
Fellowship
- 1984 - 1987
- National Jewish Health for Immunology, Allergy/Immunology
- 1983 - 1984
- Vanderbilt University (Nashville, TN), Neonatology
Board Certification
National Board Certification
Pediatric Board Certification - Written exam
Colorado Medical License
Pediatric Board Certification - Oral exam
Academy of Allergy/Immunology Board
Publications
Fernandez-Boyanapalli R, Goleva E, Kolakowski C, Min E, Day B, Riches DWH, BrattonDL*, Sutherland ER*. Obesity impairs apoptotic cell clearance in asthma. J Allergy Clin Immunol. Accepted 2012.
Frasch SC, Bratton DL. Emerging roles for lysophosphatidylserine in resolution of inflammation. Prog Lipid Res. 2012 Jul;51(3):199-207. Epub 2012 Mar 29. PMID: 22465125 [PubMed - in process] PMCID: PMC3365616 [Available on 2013/7/1]
Bratton DL, Henson PM. Neutrophil clearance: When the party’s over, cleanup begins. Trends Immunol. 32(8):350-7. Epub. Doi: 10,1016/j.it.2011.04.009. 2011.
Frasch SC, Fernandez-Boyanapalli RF, Berry KZ, Leslie CC, Bonventre JV, Murphy RC, Henson PM, Bratton DL. Signaling via macrophage G2A enhances efferocytosis of dying neutrophils by augmentation of Rac activity. J Biol Chem. 286(14):12108-22, 2011. Epub 2011 Feb 4. PMID: 21297111
Fernandez-Boyanapalli R, Frasch SC, Riches DWH, Vandivier RW, Henson PM, Bratton DL. PPAR{gamma} activation normalizes resolution of acute sterile inflammation in murine chronic granulomatous disease. Blood. Nov 25;116(22):4512-22, 2010 PMID: 20693431
Hospital Affiliations
- Children's Hospital Colorado
Academic Affiliations
Professor, University of Colorado Denver