Max Seibold, PhD
Dr. Max Seibold is a researcher who is focused on identifying genetic determinants and biomarkers of complex lung diseases like asthma and pulmonary fibrosis.
Research AreasSpecial Interests
The Seibold Lab is focused on identifying genetic determinants and biomarkers of complex lung diseases, including asthma and pulmonary fibrosis. Many of the genetic variants that influence development and severity of these lung diseases do so by altering molecular functions in specific lung cell types. His lab is focused on identifying dysregulated molecular functions in patient lung cells, by Nex-Generation sequencing technologies. Using patient cohorts the genetic determinants of these molecular changes are then mapped. The lab is also editing the genome of these lung cells to allow detailed mechanistic studies of disease variants and better understanding of how these genetic changes increase risk of disease development.
Education
Education
- 2008 - 2011
- National Jewish Health, Genetics of Pulmonary Fibrosis, Laboratory of Dr. David Schwartz
- 2001
- Southwestern Oklahoma State University, Chemistry
- 2008
- University of California-San Francisco, PhD, Pharmaceutical Sciences and Pharmacogenomics
Publications
Interleukin-13 associated epithelial remodeling correlates with clinical severity in nasal polyposis.
Kotas ME, Patel NN, Cope EK, Gurrola JG 2nd, Goldberg AN, Pletcher SD, Seibold MA, Moore CM, Gordon ED.J Allergy Clin Immunol. 2023 Feb 1:S0091-6749(23)00141-0. doi: 10.1016/j.jaci.2022.12.826. Online ahead of print. PMID: 36736797 Free article.
Possibilities and promise: Leveraging advances in transcriptomics for clinical decision making in allergic diseases.
Moore CM, Seibold MA. J Allergy Clin Immunol. 2022 Oct;150(4):756-765. doi: 10.1016/j.jaci.2022.08.016. Epub 2022 Aug 28.PMID: 36037873 Free article. Review.
Genome-wide association study in minority children with asthma implicates DNAH5 in bronchodilator responsiveness.
Joo J, Mak ACY, Xiao S, Sleiman PM, Hu D, Huntsman S, Eng C, Kan M, Diwakar AR, Lasky-Su JA, Weiss ST, Sordillo JE, Wu AC, Cloutier M, Canino G, Forno E, Celedón JC, Seibold MA, Hakonarson H, Williams LK, Burchard EG, Himes BE. Sci Rep. 2022 Jul 22;12(1):12514. doi: 10.1038/s41598-022-16488-6.PMID: 35869121 Free PMC article.
Human Epidemiology and RespOnse to SARS-CoV-2 (HEROS): Objectives, Design and Enrollment Results of a 12-City Remote Observational Surveillance Study of Households with Children using Direct-to-Participant Methods. Fulkerson PC, Lussier SJ, Bendixsen CG, Castina SM, Gebretsadik T, Marlin JS, Russell PB, Seibold MA, Everman JL, Moore CM, Snyder BM, Thompson K, Tregoning GS, Wellford S, Arbes SJ, Bacharier LB, Calatroni A, Camargo CA, Dupont WD, Furuta GT, Gruchalla RS, Gupta RS, Hershey GK, Jackson DJ, Johnson CC, Kattan M, Liu AH, Murrison L, Oâ Connor GT, Phipatanakul W, Rivera-Spoljaric K, Rothenberg ME, Seroogy CM, Teach SJ, Zoratti EM, Togias A, Hartert TV. medRxiv. 2022 Jul 10:2022.07.09.22277457. doi: 10.1101/2022.07.09.22277457. Preprint.PMID: 35860216 Free PMC article.
Teaching & Professional Positions
Professor, 2022 – present
Associate Professor, CGEH, Department of Pediatrics, National Jewish Health 2015 - 2022
Assistant Professor, CGEH, Department of Pediatrics, National Jewish Health 2011 - 2015