Advanced Diagnostic Laboratories

D-Dimer

Test Code

DDIME

Description

D-Dimer, Quantitative - D-Dimer is one of the measurable by-products of activation of the fibrinolytic system. Quantitation of D-Dimer assesses fibrinolytic activation and intravascular thrombosis. D-Dimer is of particular value in excluding the diagnosis of venous thromboembolism among patients at high risk.

Collect

Sodium Citrate Light Blue Top 3.2% sodium citrate solution -2.7 mL Vacutainer® Citrate Tubes with 3.2% buffered sodium citrate solution
BD Vacutainer® Citrate Tubes - 363080 | BD

Pediatric Collection

Fill to Minimum Fill Indicator on draw tube

Unacceptable Conditions

Clotted Specimen, Insufficient Specimen, Hemolysis

Storage Transport Temp

Storage Transport Temp

Offsite: Specimens collected offsite should be separated from cells within 2 hours of centrifugation and an aliquot placed in appropriately labeled polypropylene or similar plastic tube.

Onsite: Specimens must be transported within 1 hour to the clinical laboratory for processing and testing.

Stability

Notes

Light blue top tube requires a minimum volume to assure proper ratio of anticoagulant to whole blood

Performed

Monday - Friday

Methodology

Turbidimetric Immunoassay

Turnaround Time

1 hour STAT or routine

Department

Core Lab

Synonyms

D-Dimer, DIMER

Study Offerings

Not offered

Reference Interval

Age ≤50 years : D-Dimer, quantitative: <0.50 ug/mL FEU
Age >50 years : PE/DVT Index: Normal

Interpretation

For patients greater than 50 years old, age adjusted cutoff interpretation is applied using the calculation: age x 0.01 ug/mL FEU and reported as a qualitative PE/DVT index (Normal/Abnormal) with regards to exclusion for suspected thrombosis. Patients 50 years or older have an association with increased diagnostic yield of non-specific D-Dimer.