Autoimmune Lymphoproliferative Syndrome
Test Code
ALPS
Description
Collect
Draw one green top tube (Sodium or Lithium Heparin) top tube.
Pediatric Collection
Minimum volume: 1mL
Unacceptable Conditions
Frozen, clotted, hemolyzed or centrifuged specimens. Anticoagulants other than heparin. Specimens >24 hrs old.
Storage Transport Temp
Maintain and transport specimens at room temperature (18-22°C).
Ship specimens Priority Overnight via Fed Ex in container sufficiently insulated to avoid temperature extremes (<10°C and >37°C).
Stability
24 hours at room temperature (18-22°C)
Notes
Samples must arrive within 24 hours of draw and are accepted Monday through noon on Friday.
Performed
Tue-Fri
Methodology
Flow Cytometry
Turnaround Time
2-4 days
Department
Immunology Lab - Phenotyping Assays
Synonyms
Autoimmune lymphoproliferative syndrome;Double negative T cells
Study Offerings
RUO
CAP/CLIA
Reference Interval
<2.5% Of T Cells
Interpretation
This test is useful for assessing the percentage of CD4-CD8- (double negative) T cells or DNTs. DNT > 1% supports the diagnosis of autoimmune lymphoproliferative syndrome (ALPS).
CPT Code
88185, 88184 x 3
New York Approved
No: Run with Waiver
FDA
LDT