CD40 Ligand
Test Code
CD40L
Description
Collect
Draw one green top tube (Sodium or Lithium Heparin) top tube.
Pediatric Collection
Minimum volume: 1mL blood
Unacceptable Conditions
Frozen, clotted, hemolyzed or centrifuged specimens. Anticoagulants other than heparin. Specimens >24 hrs old.
Storage Transport Temp
Maintain and transport specimens at room temperature (18-22°C).
Ship specimens Priority Overnight via Fed Ex in container sufficiently insulated to avoid temperature extremes (<10°C and >37°C).
Stability
24 hours at room temperature (18-22°C)
Notes
Samples must arrive within 24 hours of draw and are accepted Monday through Thursday.
Performed
Tue-Fri
Methodology
Flow Cytometry
Turnaround Time
2-4 days
Department
Immunology Lab - Phenotyping Assays
Synonyms
CD154
Study Offerings
RUO
CAP/CLIA
Related Tests
CD40
Reference Interval
CD40 Ligand is expressed on stimulated lymphocytes in normal individuals.
Interpretation
- Mutations in the CD40 ligand gene are associated with X-linked hyper IgM (HIGM) syndrome. Analysis of the expression of CD40L on activated T cells assists in the diagnosis of X-linked HIGM syndrome.
- TLR
Disease Association Reference - TLR2
M. tuberculosis, S. aureus and other gram positive infect
CPT Code
86353, 88184, 88185 x 5
New York Approved
No: Run with Waiver
FDA
LDT