IgG Subclasses
Test Code
GSUB
Description
Collect
Serum from a plain red top is the only acceptable sample type.
Gel barrier tubes are not acceptable.
Specimen Preparation
Allow blood to clot at room temp or 37°C for 20 to 60 minutes. Centrifuge to thoroughly remove cells and immediately transfer cell-free serum to a fresh tube and freeze the cell-free serum on dry ice or at -70°C.
Preferred volume: 1 mL
Pediatric Collection
Minimum volume: 500 µL serum, frozen
Unacceptable Conditions
Thawed specimen.
Storage Transport Temp
Send frozen serum Priority Overnight via FedEx and in a well insulated container on dry ice.
Stability
Frozen at -70°C: 1 year
Methodology
Turbidimetry and Photometry
Reported
up to 4 weeks
Department
Complement LabSynonyms
Subclasses, IgG1, IgG2, IgG3, IgG4, total IgG, subclasses;IGSUB
Reference Interval
TEST CODE | AGE | REFERENCE RANGE (mg/dL) |
IGG1 | 0-2 | 194-842 |
2-4 | 315-945 | |
4-6 | 306-945 | |
6-8 | 288-918 | |
8-10 | 432-1020 | |
10-12 | 423-1060 | |
12-14 | 342-1150 | |
14-18 | 315-855 | |
18+ | 278.5 – 849.9 | |
IGG2 | 0-2 | 22.5-300 |
2-4 | 36.0-225 | |
4-6 | 60.5-345 | |
6-8 | 44.0-375 | |
8-10 | 72.0-430 | |
10-12 | 76.0-355 | |
12-14 | 100-455 | |
14-18 | 64.0-495 | |
18+ | 172.2-694.7 | |
IGG3 | 0-2 | 18.6-85.3 |
2-4 | 17.3-67.6 | |
4-6 | 9.9-122.1 | |
6-8 | 15.5-85.3 | |
8-10 | 12.7-85.3 | |
10-12 | 17.3-173 | |
12-14 | 28.3-125 | |
14-18 | 23.0-196 | |
18+ | 13.53-167.4 | |
IGG4 | 0-2 | 0.5-78.4 |
2-4 | 1.0-53.7 | |
4-6 | 1.8-112.5 | |
6-8 | 0.4-99.2 | |
8-10 | 1.9-93.2 | |
10-12 | 1.6-115 | |
12-14 | 3.7-136 | |
14-18 | 11.0-157 | |
18+ | 3.41-142.8 | |
Total IGG | 0-3M | 250-1200 |
3M-2Y | 286-1680 | |
2-4 | 341-1960 | |
4-20 | 528-2190 | |
20+ | 700-1620 |
CPT Code
82787x4, 82784